In echinococcosis, as additional funds for the surgical treatment Niya use Albendazole or mebendazole. As a result of disrupted education microtubes and is destroyed already formed microtubes, a result of which food is broken worms. Distinguish between intestinal and extraintestinal nematodoses, cestodosis and trematodozy. On the amoeba in the lumen of the intestine are diloksanid, hiniofon (yatren). Proguanil (bigumal) - a derivative of biguanide. Piperazine - GAMKreceptors agonist, causes hyperpolarization of the membrane of muscle worms, resulting in growing their flaccid paralysis and immobilization. In the cells of the digestive tract of the first worm is associated with the dimers tubulin, which is involved in the formation of microtubes, and prevents them in polymerization. As a result, developing spastic paralysis of the worms. Universal effect on the amoeba of any location (except for the cysts) has a derivative of nitroimidazole metronidazole. The drug is contraindicated during pregnancy and breastfeeding. The body is transformed into an active metabolite tsikloguanil, which inhibits dihydrofolate reductase. Dermal leishmaniasis preside applied mepakrin (quinacrine), intramuscularly-muscular and topical - monomitsin. Effective against preeritrotsitarnyh, Erith rotsitarnyh forms of plasmodia and gamontov. Therefore, drugs are not prescribed during pregnancy. Side effects of primaquine: nausea, vomiting, abdominal pain, acute anemia gemoliti-parameter (with a deficit глюкоза6фосфатдегидрогеназы). Derivatives of benzimidazole in the experiment have teratogenic effect. With the ineffectiveness of other antimalarials against erythro-tsitarnyh forms of plasmodia, preside in the treatment of falciparum malaria, prescribe doxycycline (an antibiotic from the group tetratsik-Linova;), artemisinin (Artemisia alkaloid) or its Derivatives - artemether, artesunate. Assign inside. Causes immobilization worms, after which the worms preside separated from the mucosa of intestinal-ka. Side effects of mefloquine: nausea, vomiting, preside headache, head-spinning, visual disturbances, neuropathy, tremor, ataxia, depression, disorientation, hallucinations, disturbances atrioventriku polar conductivity, myalgia, arthralgia, rash, alopecia, leukopenia, thrombocytopenia. In addition, praziquantel is effective in trematodozah liver (clonorchiasis, described storhoz). Side effects of proguanil: stomatitis, mouth ulcers, Sexually Transmitted Disease skin reactions, alopecia. Side effects of drugs of antimony: nausea, vomiting, abdominal pain, Percutaneous Myocardial Revascularisation of the liver, kidneys, myalgia, cough, pain in the breastbone. For both forms of leishmaniasis are used antimony drugs - sodium stiboglyukonat (solyusurmin, intravenously), and meglumine pentamidine (intramuscularly). When teniasis the drug should only be used in combination with saline laxatives to prevent preside cysticercosis. These funds are used in the form of tablets and vaginal suppozi-thorium. Praziquantel (biltritsid) increases the permeability of the membrane of the muscle-curl worms for Ca2 +. Apply piperazine in ascariasis and enterobiasis. Praziquantel is used for teniarinhoze (invasion bovine chain) teniasis (infestation of swine chain) bothriocephaliasis (invasion broad tapeworm), hymenolepiasis (dwarf invasion depnem). Ivermectin - tool of choice for strongiloidoze. By proguanil is rapidly developing resistance of Plasmodium and is now in many preside of proguanil as an antimalarial tool is not very effective. Preparation appointed interior. By cestodes (tape helminths) is considered bullish (unarmed) and pork (armed) tapeworm (Taenia saginata and T solium), broad tapeworm (Diphyllobotrium latum), dwarf tapeworm preside nana), Echinococcus (Echinococcus granulosis, E multilocularis).
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