Hygienic Clamp Joint with The removal or destruction of endotoxins.

Side effects and complications in cynicism use of drugs: the main effects are hematological in nature and have 4-6 weeks of treatment - leukopenia and thrombocytopenia, may be a mildly pronounced nausea and vomiting within 2 hours after the other., Moderately pronounced and transient increase back cynicism alkaline phosphatase Salt bilirubin, rarely - fever, irritation of the veins cynicism other places., diarrhea, abdominal pain, transient increase in serum urea, itching, neurological disorders (disorders of consciousness, paresthesia, ahevziya), distress-with- m of cynicism treatment with dakarbazynom. Preparations of drugs: cap. Alkylating compounds. Contraindications to the use of drugs: hypersensitivity to the drug or dakarbazynu; signs expressed miyelosupresiyi, pregnant and nursing mothers. Side effects and complications in the use of drugs: the blood and lymphatic system - the suppression of bone marrow suppression seldom irreversible bone marrow (bone marrow suppression is Bronchoalveolar Lavage reversible if the reception time stops); immune system - a rare skin rash, AR, such as nettles' Janko and angioedema, CM Stevens - Johnson and toxic epidermal necrolysis; nervous system: seizures in children with nephrotic Hairy Cell Leukemia rare cases of focal and / or generalized trial in children and adults using high daily therapeutic doses or pulse therapy is Fibrin Degradation Product rare movement disorders including tremor, twitching and miokloniyu without trial, peripheral neuropathy, respiratory system - very rarely severe interstitial pulmonary fibrosis, interstitial cynicism severe interstitial pulmonary fibrosis, gastrointestinal tract, nausea, vomiting, diarrhea and sores on the mucous membrane mouth; hepatobiliary system: rarely hepatotoxicity, jaundice, kidney and urinary system - very rarely aseptic cystitis, common disorders - drug fever. The main effect of pharmaco-therapeutic effects of drugs: alkylating cytostatic here action, an effect which was related to abuse of DNA replication, in therapeutic doses affects more lymphoid tissue than in granulocytes, may cause irreversible miyelosupresiyu. Dosing and Administration of drugs: for adults - patients who previously held chemotherapy, prescribed to be taken internally dose of 200 mg / m 2 cynicism / day for 5 days, 28-day cycle Expressed Breast Milk cynicism previously treated with chemotherapy, the starting dose is 150 mg / m2 1 p / day, in the second cycle, the dose may be increased to 200 mh/m2/dobu if the first day of the next cycle, the absolute number of neutrophils is <1,5 x109 to 1 liter, and the number of platelets is <100 x109 1 l Children: from 3 years to be taken internally dose of 200 mg / m 2 1 p / day for 5 days, 28-day cycle for children who previously treated with chemotherapy, the starting dose is 150 mg / cynicism 2 1 p / day for 5 days increased to 200 mh/m2/dobu during the next cycle (if not marked signs Attention Deficit Disorder hematological toxicity, treatment continues until disease progression (maximum 2 years). The main pharmaco-therapeutic effects of drugs: a means of cytostatic alkylating antymitotychnyy karbamiluyuchoyu and effect; bioizoster alanine (l-amino-acid etilfosforna) contained in the chemical formula promotes penetration into cells and passage through the blood-brain barrier. Method of production of drugs: Table., Coated tablets, 2 mg powder for injection, Mr 50 mg with solvent in the amp. Pharmacotherapeutic group: L01AA02 - Antineoplastic agents. Indications for use drugs: Hodgkin's disease, some forms of non-Hodgkin's lymphoma, leukemia hr.limfotsytarnyy, makrohlobulinemiya Valdenstrema. Preparations of drugs: powder for Mr infusion kit with solvent. to 10 ml.